Gastric cancer with peritoneal metastases has a dismal prognosis. Cytoreductive surgery (CRS) is effective, but the impact of hyperthermic intraperitoneal chemotherapy (HIPEC) remains controversial. A French multicentric study  compared the effect of adding HIPEC to surgery alone in 277 patients. The study, which was published in one of the best cancer journals, shows that additional HIPEC improved survival without additional complications or death cases. However, results of this study can only be applied to strictly selected patients with limited extent of peritoneal metastasis.

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