On Nov 7th, 2019 the first PIPAC in Brazil was performed by Dr Roberta Lages Merces, Dr Yumiko Akaishi and Dr Antonio Macedo at the Hopital Nova Star in Sao Paolo. The physicians had been previously trained in the PIPAC indications, technique and occupational safety measures in an ISSPP course in Montpellier (France) under the lead of Dr. Olivia Sgarbura.