Interview with Prof Jimmy So, from the National University Singapore.
Prof. Jimmy So will explain the results of the Extensive Peritoneal Lavage after curative gastrectomy for gastric cancer (EXPEL) study he presented recently at the Gastrointestinal Cancers Symposium 2020 (ASCO GI) in San Francisco. The EXPEL trial is a prospective randomized, high-quality surgical study evaluating the potential benefit of peritoneal lavage after surgical resection of the stomach. The trial involved 800 patients from 22 hospitals from Korea, China, Japan, Malaysia, and Singapore. Patients with cT3, T4 stomach cancer undergoing curative resection were randomized to surgery alone (control group, n=402 patients) or surgery followed by lavage of the peritoneal cavity with 10 L of saline solution (test group, n=398 patients). There was no difference in the 3-year cumulative incidence of recurrence between the two groups. The rate of adverse events was higher in the test group (RR=1.58, P=0.019).